Description
Product Characteristics:
Aliases: Homeobox protein meis3 antibody, Meis homeobox 3 antibody, Meis1 myeloid ecotropic viral integration site 1 homolog 3 antibody, Meis1 related protein 2 antibody, Meis1-related protein 2 antibody, meis3 antibody, MEIS3_HUMAN antibody, MRG2 antibody
Target Information: Caudalizing protein which is required to pattern the anterior/posterior (A/P) axis during central nervous system (CNS) formation. Inhibits anterior neural expression and acts as a transcriptional activator to induce posterior neural gene expression. Maintains a proper A/P balance required for hindbrain formation by activating the FGF/MAPK pathway, which modulates the planar cell polarity (PCP) pathway. Interacts with retinoid signaling during hindbrain patterning